Osteoprotegerin ELISA

The Osteoprotegerin (OPG) ELISA kit is a sandwich ELISA intended for the quantitative determination of osteoprotegerin in serum, EDTA plasma, heparin plasma or citrate plasma. 

Osteoprotegerin (OPG) or osteoclast inhibitory factor (OCIF) is a glycoprotein produced by many different tissues and cell types including osteoblasts.

OPG is a negative regulator of bone resorption by acting as decoy receptor for RANKL, thus neutralizing its function in osteoclastogenesis. This glycoprotein is also involved in the regulation of vascular calcification.