Prealbumin (transthyretin) ELISA

The Prealbumin (transthyretin) ELISA kit is intended for the quantitative determination of prealbumin (transthyretin) in serum, plasma, urine and stool. 

Prealbumin (transthyretin) is a transport protein secreted in the liver, brain and retina. It transports thyroxin (T4) and retinol binding protein in serum and cerebrospinal fluid. 

Transthyretin is reduced in inflammatory reactions and is therefor an acutephase protein. A mutation in the transthyretin gene can result in a chronically lowered transthyretin level in the blood, leading to amyloidosis. As transthyretin is the protein with the highest proportion of essential amino acids and has a rather short biological halflife of 1–2 days, it can be used for the diagnosis of malnourishment and distur-bances of the metabolic pathways in the liver.