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The α2-Macroglobulin ELISA kit is intended for the quantitative determination of α2-macroglobulin in urine, serum and plasma. 

Indications:

• Detection and differentiation of proteinuria according to kidney damage localisation;

• Differentiation of renal and postrenal hematuria.

Detecting α2M in urine is evidence of postrenal damage, when unfiltered serum proteins leak into the urine. Causes of postrenal damage are inflammation or hematuria as a consequence of renal stones or carcinomas.

The β-Defensin 2 ELISA kit is intended for the quantitative determination of β-defensin 2 in stool. 

Defensins exert a variable degree of antimicrobial activity against bacteria, fungi, and some enveloped viruses. The expression of ß-defensins is induced by the proinflammatory cytokines and also through microorganisms (e.g. E. coli, H. pylori or P. aeruginosa).

A ß-defensin 2 deficiency can, for example, be observed in the intestinal mucous of patients with Crohn’s disease. 

The Pancreatic amylase ELISA kit is an enzyme immunoassay intended for the quantitative determination of pancreatic amylase in stool. 

Like lipase and elastase, the pancreatic amylase is synthesised in the pancreas. In case of a chronic pancreatitis, pancreatic amylase is decreased.

Indications:

• Chronic pancreatitis;

• Exocrine pancreatic insufficiency.

The Prealbumin (transthyretin) ELISA kit is intended for the quantitative determination of prealbumin (transthyretin) in serum, plasma, urine and stool. 

Prealbumin (transthyretin) is a transport protein secreted in the liver, brain and retina. It transports thyroxin (T4) and retinol binding protein in serum and cerebrospinal fluid. 

Transthyretin is reduced in inflammatory reactions and is therefor an acutephase protein. A mutation in the transthyretin gene can result in a chronically lowered transthyretin level in the blood, leading to amyloidosis. As transthyretin is the protein with the highest proportion of essential amino acids and has a rather short biological halflife of 1–2 days, it can be used for the diagnosis of malnourishment and distur-bances of the metabolic pathways in the liver.

The Albumin ELISA kit is an enzyme immunoassay intended for the quantitative determination of albumin in urine and stool.

Albumin is the major protein in human plasma. Changes in the concentration of albumin in urine and faeces are a result of distribution disorder, less synthesis problems. Stronger albumin loss leads to increased synthesis, for example in case of nephrotic syndrome.

Elevated levels of albumin and hemoglobin in stool are observed not only in colorectal carcinomas, but also in polyps and during chronic inflammatory diseases (Morbus Crohn or Colitis Ulcerosa). Albumin in faecal samples refers to an inflammatory reaction combined with intestinal bleeding. 

The Adiponectin (total) ELISA kit is an enzyme immunoassay intended for the quantitative determination of adiponectin in serum and plasma. 

Adiponectin levels are associated with insulin resistance and, accordingly, are associated with type 2 diabetes. The higher the level of adiponectin in the blood, the lower the risk of developing type 2 diabetes, regardless of body mass index (BMI), race and gender.

In addition, it is involved in inflammatory processes and, therefore, is important for the development of atherosclerosis and coronary artery disease.

The Hemoglobin ELISA kit is designed to quantify human hemoglobin (Hb) in stool (colorectal cancer screening).

Indications:

• Crohn's disease; Ulcerative Colitis;

• Suspicion of colon carcinoma;

• Polyps in the colon.

The Hb / Hp complex ELISA kit is designed to quantify the hemoglobin / haptoglobin (Hb / Hp) complex in human stool.

Hemoglobin/haptoglobin complex determination increases the clinical specificity and sensitivity.

Indications:

• Crohn's disease; Ulcerative Colitis;

• Suspicion of colon carcinoma;

• Polyps in the colon.

The Nitrotyrosine ELISA kit is an enzyme immunoassay intended for the quantitative determination of protein-bound nitrotyrosine in human EDTA-plasma, serum and dried blood spots. 

The accumulation of protein bound nitrotyrosine is associated with cardiovascular diseases that are based on inflammatory processes (e. g., atherosclerosis, myocardial infarction, diabetic vasculopathy, hypertension, or coronary heart diseases).

A growing number of studies have also associated the accumulation of nitrotyrosine with neurological diseases (Alzheimer´s disease, Parkinson´s disease, multiple sclerosis, stroke). 

Nitrotyrosine is a stable product and might be seen as a correlate of peroxynitrite production, and its accumulation in cells and tissues is a marker of oxidative stress and nitrosative stress, respectively.

The Nitrotyrosine ELISA kit is an enzyme immunoassay intended for the quantitative determination of protein-bound nitrotyrosine in EDTA plasma, serum and stool.

The accumulation of protein bound nitrotyrosine is associated with cardiovascular diseases that are based on inflammatory processes (e. g., atherosclerosis, myocardial infarction, diabetic vasculopathy, hypertension, or coronary heart diseases).

A growing number of studies have also associated the accumulation of nitrotyrosine with neurological diseases (Alzheimer´s disease, Parkinson´s disease, multiple sclerosis, stroke). 

Nitrotyrosine is a stable product and might be seen as a correlate of peroxynitrite production, and its accumulation in cells and tissues is a marker of oxidative stress and nitrosative stress, respectively.

The Intact Proinsulin ELISA Kit is an enzyme immunoassay intended for the quantitative determination of intact proinsulin in serum and plasma.

Proinsulin is a precursor molecule for insulin and is synthesised by the pancreatic β-cells.

Indications:

• Diabetes type 1 and 2;

• Insulinomas, functional hypoglycemia, hyperinsulinemia;

• Kidney dysfunction, cirrhosis and hyperthyreosis;

• Cardiovascular diseases.

The CRP ELISA kit is a enzyme immunoassay intended for the quantitative determination of C-reactive protein in plasma, serum, stool, dried blood spots, and urine. 

Studies describe an association between inflammatory reactions and cardiovascular diseases like arteriosclerosis or latent and chronic persistent infections. As a marker for inflammation, CRP high-sensitive can be used to predict the risk of myocardial infarction and stroke. 

The CRP determination in urine allows – together with a2-macroglobulin – an early screening after kidney transplantations. 

The CRP ELISA kit is a enzyme immunoassay intended for the quantitative determination of C-reactive protein in plasma, serum, stool, dried blood spots, and urine. 

Studies describe an association between inflammatory reactions and cardiovascular diseases like arteriosclerosis or latent and chronic persistent infections. As a marker for inflammation, CRP high-sensitive can be used to predict the risk of myocardial infarction and stroke. 

The CRP determination in urine allows – together with a2-macroglobulin – an early screening after kidney transplantations. 

The ADMA ELISA kit is intended for the quantitative determination of asymmetric dimethyl-L-arginine (ADMA) in human serum, citrate and EDTA plasma. 

Elevated ADMA concentrations in the blood are found in numerous diseases associated with endothelial dysfunction. For example, elevated ADMA levels in blood of dialysis patients correlate significantly with the degree of arteriosclerosis and cardiovascular risk.

Furthermore, elevated ADMA levels are found in patients with hypercholesterolemia, hypertension, arteriosclerosis, chronic renal failure and chronic heart failure, and are associated with restrictions in endothelial vasodilatation. 

The SDMA ELISA kit is intended for the quantitative determination of symmetrical dimethyarginine (Symmetrical dimethylarginine (SDMA)) in human, canine and feline serum, EDTA and Li-heparin plasma.

SDMA is a methylated derivative of L-arginine which is strictly eliminated by renal extraction, thus the SDMA plasma level is strongly correlated to renal function. 

Indication:

· Renal failure;

· Cardiovascular risk in renal dysfunction;

· Hypertension in renal dysfunction.